A modern view on the treatment of acute bronchiolitis in pediatric intensive care units: a review

INTRODUCTION. The literature has accumulated enough data on the treatment of children with acute bronchiolitis (OB). However, this information is formed mainly general population patients OB and often not applicable to a severe course disease. From standpoint evidence-based medicine, routine use medications recommended in modern consent documents, there are also no clear recommendations respiratory support certain aspects intensive care OB. OBJECTIVES. To analyze approaches therapy need care, assess validity, effectiveness safety analyzed groups drugs strategies. MATERIALS AND METHODS. analysis publications electronic databases PubMed Russian Scientific Citation Index keywords “bronchiolitis”, “intensive units”, “critical care”, “fluid therapy”, “respiratory “ventilation”, “co-morbidity”; syncytial virus”; “hypertonic saline” was carried out, “corticosteroids”; “epinephrine”; “high-flow oxygen “inhalation”, “infant”, “bronchiolitis children”. date last search January 15, 2022. RESULTS. This systematic review provides etiology risk factors syndrome children, from studies characterized, including unit glucocorticosteroids, inhalations bronchodilators, epinephrine, 3 % hypertonic sodium chloride solution, support, high-flow oxygenation, noninvasive ventilation, artificial antibiotics, air-helium mixture. CONCLUSIONS. Currently, more that infants show high degree heterogeneity, while main uncertainty lies misunderstanding processes, which will benefit most particular method. Further research needed fill deficit